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Benzhydrocodone
go.drugbank.com/drugs/DB15465Approved[L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse. … It was first approved by the FDA in February 2018 in combination with [acetaminophen] under the trade name Apadaz, marketed by KVK Tech and developed by KemPharm.[L7859,L7862]
Gallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalpositive lesions in men with prostate cancer. … [L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.
Categories: Compounds used in a research, industrial, or household settingMelperone
go.drugbank.com/drugs/DB09224InvestigationalIt has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile. … Melperone has been used for a span of greater than 30 years in the European Union [L1316].
Categories: Dopamine D2 Receptor AntagonistsIoxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnLike other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during angiography, arteriography … This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures.
Categories: Compounds used in a research, industrial, or household settingIohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideSulisobenzone
go.drugbank.com/drugs/DB11185ApprovedSulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. … Benzophenones may be found organically in fruits such as grapes [L2669].
Mixtures: Rayito de Sol, Rayito de SolInternational brands: Uvinul D 5030Ethinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigationalEthinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability. … [A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.
Mixtures: ACTIVA DE +TABLETAS RECUBIERTAS, ADELLA MINI TABLETA CON RECUBRIMIENTO DE GELATINAProducts: ETINILESTRADIOLO E DROSPIRENONE DOC, LEVONORGESTREL E ETINILESTRADIOLO AUROBINDOTrastuzumab deruxtecan
go.drugbank.com/drugs/DB14962ApprovedInvestigational[A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and was first approved by the FDA in 2019.[L10842] … [L10842] It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class.
Oxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. … [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning.
Products: Oxyla 10 IU/mL Injection, SYNTOCINON INJECTION 10 iu/mlTocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalTocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E. … The classification of the tocopherol molecules is designated depending on the number and position of the methyl substituent in the chromanol ring.
Mixtures: Vital-D Rx, RenaPlex-DCategories: Vitamin E, tocopherol (vit E)