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Displaying results 121 - 130 of 9754 in total
  1. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.
  2. Drug

    Fasitibant

    go.drugbank.com/drugs/DB15646
    Investigational

    Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).

    Salts: Fasitibant chloride, Fasitibant chloride hydrochlorideCategories: Amino Acids, Peptides, and Proteins
  3. Drug

    Chelerythrine

    go.drugbank.com/drugs/DB17024
    Experimental

    A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.

    Salts: Chelerythrine chloride
  4. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  5. Drug

    Acriflavine

    go.drugbank.com/drugs/DB13373
    Investigational

    Salts: Acriflavinium chlorideCategories: acriflavinium chloride, Indicators and Reagents
  6. Drug

    Gantacurium

    go.drugbank.com/drugs/DB05710
    Investigational

    Gantacurium chloride is a new, investigational, non-depolarizing ultra-short acting neuromuscular blocker. It is being developed by Avera Pharmaceuticals.

    Salts: Gantacurium chloride
  7. Drug

    Samarium

    go.drugbank.com/drugs/DB12403
    Investigational

    Samarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate Cancer, and Metastatic Osteosarcoma, among others.

    Salts: Samarium Chloride
  8. Drug

    N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium

    go.drugbank.com/drugs/DB03945
    Investigational

    Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

    Salts: Phosphorylcholine chloride
  9. Drug

    Lysozyme

    go.drugbank.com/drugs/DB13260
    Investigational

    Salts: Lysozyme chlorideCategories: Enzymes and Coenzymes
  10. Drug

    Diphenyleneiodonium

    go.drugbank.com/drugs/DB17025
    Experimental

    An NADPH oxidase 2 (NOX2) inhibitor.[A252987]

    Salts: Diphenyleneiodonium chloride