Diphenyleneiodonium

DB17025ExperimentalSmall molecule

An NADPH oxidase 2 (NOX2) inhibitor.

Chemical structure of Diphenyleneiodonium
Formula / weight
C12H8I · 279.1 g/mol (avg)
Also known as
Dibenziodolium

Resolves to

Compound
UNII6HJ411TU98CAS244-54-2ChEMBLCHEMBL365739ChEBI77986
Structure
InChIKeyQFXKXRXFBRLLPQ-UHFFFAOYSA-NSMILES[I+]1C2=CC=CC=C2C2=C1C=CC=C2
Targets
P35228NOS2P16435PORP04839CYBB

What you can answer from here — as of July 17, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
10+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Diphenyleneiodonium, and which of those have an active Phase 3 trial?

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