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Vasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalthrough V<sub>1</sub> and V<sub>2</sub> cellular receptors. … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]
Products: VASOPRESSIN INJECTION USP 20 u/ml, VASOPRESINA INYECTABLE 20 U/ML USPInterferon alfacon-1
go.drugbank.com/drugs/DB00069ApprovedWithdrawnInterferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. … Interferon alfacon-1 is produced in Escherichia coli (E. coli) cells that have been genetically altered by insertion of a synthetically constructed sequence that codes for Interferon alfacon-1.
Categories: Interferon Type I, interferon alfacon-1Synonyms: IFN Alfacon-1, Interferon alfacon-1Trastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigational-2 protein in tumours. … [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER
Mixtures: PHESGO® 600MG/600MG, PHESGO® 600MG/600MGCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsMuromonab
go.drugbank.com/drugs/DB00075ApprovedInvestigationalWithdrawnMore specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. … Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).
Categories: Immunoglobulin GProducts: Orthoclone Okt 3 Sterile Solution IV 1mg/mlTositumomab
go.drugbank.com/drugs/DB00081ApprovedWithdrawnMurine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. … It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Streptokinase
go.drugbank.com/drugs/DB00086ApprovedInvestigationalWithdrawnStreptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Products: Streptokinase Karma 1 500 000 IU Powder for Solution for InfusionCapromab pendetide
go.drugbank.com/drugs/DB00089ApprovedWithdrawnCapromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate … When linked to pendetide, capromab is used as a chelating agent for the radionuclide [Indium In-111] during imaging to evaluate the extent of prostate cancer.
Categories: Compounds used in a research, industrial, or household settingAlefacept
go.drugbank.com/drugs/DB00092ApprovedWithdrawnImmunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of
Categories: CD2-directed LFA-3/Fc Fusion ProteinCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100Approvedmedium that is then processed and purified for use as a pharmaceutical agent. … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.
Products: OCTANINE® F 500 UI, OCTANINE F ® 250 UIBecaplermin
go.drugbank.com/drugs/DB00102ApprovedInvestigationalBecaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds. … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae.
Categories: Proto-Oncogene Proteins c-sisSynonyms: PDGF-2