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Displaying results 121 - 130 of 157438 in total
  1. Drug

    Mebutamate

    go.drugbank.com/drugs/DB06797
    Approved

    Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a

    Synonyms: 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate, 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate
  2. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.

    Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, ABACAVIR 600 MG Y LAMIVUDINA 300 MGCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Mitoxantrone

    go.drugbank.com/drugs/DB01204
    ApprovedInvestigational

    An anthracenedione-derived antineoplastic agent.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexSynonyms: 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone
  4. Drug

    Elacestrant

    go.drugbank.com/drugs/DB06374
    ApprovedInvestigational

    [L44918,L44948] It received a similar approval in the EU in September 2023. … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol, (6R)-6-(2-(ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen-2-ol
  5. Drug

    Rotigotine

    go.drugbank.com/drugs/DB05271
    ApprovedInvestigational

    It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. … Rotigotine has been authorized as a treatment for RLS since August 2008.

    Mixtures: NEUPRO TRANSDERMAL 28 FLASTER BASLANGIC TEDAVI PAKETI, NEUPRO TRANSDERMAL 28 FLASTER BASLANGIC TEDAVI PAKETICategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate, 5-(propylthio)-2-carbomethoxyaminobenzimidazoleInternational brands: Ben-A
  7. Drug

    Famciclovir

    go.drugbank.com/drugs/DB00426
    ApprovedInvestigational

    Famciclovir is a prodrug of penciclovir with higher oral bioavailability. … Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate, acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester
  8. Drug

    Telmisartan

    go.drugbank.com/drugs/DB00966
    ApprovedInvestigational

    smooth muscle, ultimately leading to a reduction in arterial blood pressure. … Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular

    Mixtures: RENANGIO PLUS®80 MG + 25 MG, MICARDIS® PLUS 80 MG/25 MGCategories: Angiotensin 2 Receptor Blocker, Heterocyclic Compounds, 2-Ring
  9. Drug

    Benzonatate

    go.drugbank.com/drugs/DB00868
    ApprovedInvestigational

    [A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. … [L11193] Although it not prone to drug misuse or abuse, benzonatate is associated with a risk for severe toxicity and overdose, especially in children.[A189513]

    Synonyms: 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoate, 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl p-(butylamino)benzoateProducts: Benzonatate 100 mg, Benzonatate 200 mg
  10. Drug

    Bronopol

    go.drugbank.com/drugs/DB13960
    Approved

    Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. … The agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-nitropropane-1,3-diol, 2-Nitro-2-bromo-1,3-propanediol