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Butylene glycol
go.drugbank.com/drugs/DB14110ApprovedProducts: PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU, Dr.g A-clear Balancing TonerIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.
Mixtures: Ag-irbesartan Hctz, Ag-irbesartan HctzCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsMoroctocog alfa
go.drugbank.com/drugs/DB13999Approveda co-factor to Factor IX. … Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of
Products: REFACTO AF, Refacto AFZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigationalZolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent the current "gold standard" for acute migraine treatment.
Categories: Monoamine Oxidase A Substrates, Cytochrome P-450 SubstratesProducts: Ag-zolmitriptan ODT, ZOLMITRIPTAN AL 5MGClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedAs well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … well as athlete's foot [A174097].
Mixtures: SAEROGENTA-A CREAMCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsPheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine]. … [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs.
Mixtures: Opcon-A, Opcon-AProducts: FENİRAMİN-PF 45,5 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 FLAKON, AVIL 45,5 MG/2 ML IM/IV AMPUL, 5 MLTuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with *Mycobacterium tuberculosis* through early diagnosis and appropriate
Categories: Compounds used in a research, industrial, or household settingProducts: Tuberculin PPD RT 23 AJV, TUBERCULIN PPD RT 23 AJVLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: A D, Imodium ADBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: BENAZEPLUS AL 20MG/25MG, BENAZEPLUS AL 10MG/12.5MGProducts: BENAZEPRIL AL 5MG FILMTAB, BENAZEPRIL AL 10MG FILMTABDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Ag-doxycycline, DOXYCYCLIN AL 100