Sodium fluorophosphate

DB09484ApprovedInvestigationalSmall molecule

Sodium fluorophosphate is a fluoride anticaries agent used to prevent and treat dental cavities. Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

Chemical structure of Sodium fluorophosphate
Mechanism
Curator reviewed
Primary indication
Sodium monofluorophosphate is indicated for the treatment of cavitiesCurator reviewed · 1 structured indication
Formula / weight
FNa2O3P · 143.949 g/mol (avg)
First approval
Canada, 1997
Also known as
Disodium phosphorofluoridate · Na MFP · NaMFP · Sodium monofluorophosphate

Resolves to

Compound
UNIIC810JCZ56QCAS10163-15-2ChEMBLCHEMBL1908359ChEBI86431KEGGD05864
Clinical / RWD
RxNorm56501ATCA01AA02ATCA12CD02
Structure
InChIKeyBFDWBSRJQZPEEB-UHFFFAOYSA-LSMILES[Na+].[Na+].[O-]P([O-])(F)=O

What you can answer from here — as of September 12, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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401Drug interactionsStructured to mechanism, not free text
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33Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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727Marketed productsAcross 3 countries and 219 labellers
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2ATC codesIncluding every combination product, plus 20 drug categories
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6+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Sodium fluorophosphate, and which companies have late-stage candidates in those indications?

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