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Displaying results 121 - 130 of 10000 in total
  1. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.

    Synonyms: (S)-Pregn-4-en-3,20-dione, (S)-4-Pregnene-3,20-dioneMixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%, Minoxidil 7% / Progesterone 0.1%
  2. Drug

    Azathioprine

    go.drugbank.com/drugs/DB00993
    ApprovedInvestigational

    [L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
  3. Drug

    Levofloxacin

    go.drugbank.com/drugs/DB01137
    ApprovedInvestigational

    [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].

    Synonyms: (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acidMixtures: TRILEVO 500 MG+30 MG+ 1000 MG TEDAVİ PAKETİ
  4. Drug

    Atracurium

    go.drugbank.com/drugs/DB13295
    ApprovedInvestigationalWithdrawn

    Categories: Heterocyclic Compounds, 2-RingProducts: TRACRİUM 25 MG/2.5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, NEUCURIUM 25 MG/2.5 ML IV INFUZYON VE ENJEKSIYON ICIN COZELTI ICEREN AMPUL, 5 ADET
  5. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. … Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.

    Synonyms: d-psi-2-Methylamino-1-phenyl-1-propanol, (+) threo-2-(methylamino)-1-phenyl-1-propanolMixtures: Zodryl DEC 25, Zodryl DAC 25
  6. Drug

    Magnesium salicylate

    go.drugbank.com/drugs/DB01397
    Approved

    Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate … Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations.

    Categories: Non COX-2 selective NSAIDSProducts: Back-ese M Tablets 325 mg, Back-ese M Tab 325mg
  7. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.

    Synonyms: (±)-2-(p-isobutylphenyl)propionic acid, 2-(4-isobutylphenyl)propanoic acidInternational brands: Act-3, Alges-X
  8. Drug

    Atomoxetine

    go.drugbank.com/drugs/DB00289
    ApprovedInvestigational

    More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate … (NMDA) receptor,[A18263] indicating a role for the glutamatergic system in the pathophysiology of ADHD.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: ATTENTHO®25 MG CAPSULAS, ACEPTOL ® 25 MG CAPSULAS
  9. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.

    Synonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  10. Drug

    Risankizumab

    go.drugbank.com/drugs/DB14762
    ApprovedInvestigational

    [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. … Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23).

    Categories: Interleukin-23 Antagonist, Interleukin-23 Subunit p19Products: Skyrizi 75 mg solution for injection in pre-filled syringe, Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET