This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Atracurium is a neuromuscular blocker indicated to relax muscles during mechanical ventilation under general anesthesia or intubation.

Generic Name
Atracurium
DrugBank Accession Number
DB13295
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental, Investigational
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
1,2-BenzodiazepineThe risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Atracurium.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Atracurium.
AcetophenazineThe risk or severity of adverse effects can be increased when Acetophenazine is combined with Atracurium.
AcetyldigitoxinThe risk or severity of Cardiac Arrhythmia can be increased when Atracurium is combined with Acetyldigitoxin.
AclidiniumAtracurium may increase the central nervous system depressant (CNS depressant) activities of Aclidinium.
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Atracurium.
AlfentanilThe risk or severity of adverse effects can be increased when Atracurium is combined with Alfentanil.
AlimemazineThe risk or severity of adverse effects can be increased when Alimemazine is combined with Atracurium.
AlloinThe therapeutic efficacy of Alloin can be decreased when used in combination with Atracurium.
AlmotriptanThe risk or severity of adverse effects can be increased when Almotriptan is combined with Atracurium.
Interactions
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Food Interactions
Not Available

Products

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Categories

ATC Codes
M03AC04 — Atracurium
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
2GQ1IRY63P
CAS number
64228-79-1
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

References

General References
  1. TITCK Product Information: Neucurium (atracurium besylate) solution for injection [Link]
RxNav
1218
Wikipedia
Atracurium_besilate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedDiagnosticAtracurium / Cefazolin / Morphine / Nadroparin / Obese1
4CompletedPreventionKidney Diseases / Prostate Hypertrophy1
4CompletedSupportive CarePost Operative Nausea and Vomiting (PONV) / Postoperative pain1
4CompletedSupportive CareQuality of Ocular Akinesia (Onset and Duration)1
4CompletedTreatmentNeuromuscular Blockade / Regional Anesthesia1
4CompletedTreatmentTracheal Intubation1
4Unknown StatusOtherPatients Undergoing Laparoscopic Surgery1
4Unknown StatusTreatmentAnaesthesia therapy1
4Unknown StatusTreatmentMyoclonus1
3CompletedDiagnosticPostoperative pain1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravenous50 mg
Injection, solutionIntravenous
InjectionIntravenous
Injection, solutionIntravenous25 MG/2.5ML
Injection, solutionIntravenous50 MG/5ML
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at June 23, 2017 20:39 / Updated at June 02, 2021 20:03