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Displaying results 121 - 130 of 514 in total
  1. Drug

    Risankizumab

    go.drugbank.com/drugs/DB14762
    ApprovedInvestigational

    [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.

  2. Drug

    Butriptyline

    go.drugbank.com/drugs/DB09016
    ApprovedWithdrawn

    Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.

  3. Indication

    Tuberous Sclerosis Complex with Renal angiomyolipoma

    go.drugbank.com/conditions/DBCOND0025534
    Drugs: Everolimus
    Synonyms: Tuberous Sclerosis Complex with Renal angiomyolipoma
  4. Drug

    Inositol nicotinate

    go.drugbank.com/drugs/DB08949
    ApprovedWithdrawn

    Inositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe intermittent claudication and Raynaud’s phenomenon. … It is associated with reduced flushing compared to other vasodilators by being broken down into the metabolites and inositol at a slower rate.

    Categories: Vitamin B Complex
  5. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0001495
    TargetAchromobacter cycloclastes

    Polypeptides: Copper-containing nitrite reductaseFunction: copper ion binding
  6. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0002802
    TargetAlcaligenes xylosoxydans xylosoxydans

    Polypeptides: Copper-containing nitrite reductaseSynonyms: Dissimilatory copper-containing nitrite reductase
  7. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  8. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  9. Drug

    Safinamide

    go.drugbank.com/drugs/DB06654
    ApprovedInvestigational

    It was approved in Europe in February 2015, and in the United States on March 21, 2017.

  10. Drug

    Pixofisiran

    go.drugbank.com/drugs/DB17294
    Experimental

    Synonyms: Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u) (1:1)