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Alendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959].
Categories: Bone Density Conservation Agents, Drugs for Treatment of Bone DiseasesEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901]
Categories: Bone Density Conservation Agents, Drugs for Treatment of Bone DiseasesBrensocatib
go.drugbank.com/drugs/DB15638ApprovedNon-cystic fibrosis bronchiectasis (NCFB) is a chronic lung disease characterized by airway widening, mucus accumulation, and neutrophilic inflammation. … [A274348] Brensocatib was approved by the US FDA on August 12, 2025, for use in adults and pediatric patients with NCFB.[L53808,L53813]
Choline C-11
go.drugbank.com/drugs/DB09563ApprovedCholine C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized
Risankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigational[L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.
Fluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalIts primary indication is for bone imaging. … Increased deposition around joints can occur in arthritis and following trauma and increased deposition in bone has been noted around fracture sites, in osteomyelitis, fibrous dysplasia, spondylitis tuberculosa
Synonyms: Fluoride ion F-18Burosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalIt causes impaired bone growth and development in children and adolescents and issues with bone mineralization throughout a patient’s life [L2346]. … Most children with XLH suffer from bowed or bent legs, short stature, bone pain and severe dental pain.
Categories: Drugs for Treatment of Bone Diseases, Drugs Affecting Bone Structure and MineralizationAbaloparatide
go.drugbank.com/drugs/DB05084ApprovedInvestigational[A256778] Abaloparatide is an osteoanabolic agent that stimulates bone formation. … [L740] It was first approved by the FDA on April 28, 2017,[A256748] for the treatment of osteoporosis in postmenopausal women and is also used to increase bone density in men with osteoporosis.
Categories: Bone Density Conservation AgentsXimelagatran
go.drugbank.com/drugs/DB04898ApprovedWithdrawnXimelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.
Mirvetuximab soravtansine
go.drugbank.com/drugs/DB12489ApprovedInvestigational[L43967,L43972] It was subsequently granted full approval in March 2024.[L50306] In October 2024, it was approved in the EU for the same indication. [L52640] … breast and non-small-cell lung cancers.