Search

Displaying results 121 - 130 of 10000 in total
  1. Drug

    Estrone sulfate

    go.drugbank.com/drugs/DB04574
    Approved

    Estrone sulfate (as estropipate) is a form of estrogen. … postmenopausal women), treatment of prostate cancer and prevention of osteoporosis.

    Synonyms: Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate, Estrone 3-sulfateMixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and Methyltestosterone
  2. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist. … Linaclotide was first approved by the FDA on August 30, 2012.[A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013,[L47221] respectively.

    Synonyms: -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1->6),(2->10),(5->13)-TRIS(DISULFIDE), (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDECategories: Alimentary Tract and Metabolism, Guanylate Cyclase-C Agonist
  3. Drug

    Boldenone undecylenate

    go.drugbank.com/drugs/DB14639
    ExperimentalIllicitVet approved

    Synonyms: 17beta-Hydroxyandrosta-1,4-dien-3-one 10-undecenoate, Boldenone 10-undecenoateCategories: Hormones, Hormone Substitutes, and Hormone Antagonists
  4. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. … Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia.

    Synonyms: 5-Carbamoyl-5H-dibenz(b,f)azepine, 5-carbamoyl-5H-dibenz[b,f]azepineCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index
  5. Drug

    Bumetanide

    go.drugbank.com/drugs/DB00887
    ApprovedInvestigational

    Bumetanide is a sulfamyl diuretic.

    Synonyms: 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid, 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acidMixtures: BURINEX TABLET 1 mg, BURINEX TABLET 1 mg
  6. Drug

    Hexaminolevulinate

    go.drugbank.com/drugs/DB06261
    ApprovedInvestigational

    Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as an optical imaging agent for use in combination with the … of a prior cystoscopy.

    Synonyms: Hexyl 5-amino-4-oxopentanoate hydrochloride, Hexyl(5-amino-4-oxopentanoat)-hydrochloridCategories: Amino Acids, Peptides, and Proteins
  7. Drug

    Trimethoprim

    go.drugbank.com/drugs/DB00440
    ApprovedInvestigationalVet approved

    [L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … prevents the synthesis of bacterial DNA and ultimately continued bacterial survival.

    Synonyms: 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamineMixtures: SEPTRIN IV 5 ML 10 AMPUL, METOPRIM 200 MG + 40 MG/5 ML SUSPANSIYON, 100 ML
  8. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. … [A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992. This medication was later discontinued from the market in 1998.[L1113]

    Synonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridineCategories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and Nucleosides
  9. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.

    Synonyms: 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide, (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamideMixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTA
  10. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.

    Synonyms: 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid, 4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acidMixtures: ILTUXAM ® 20 MG - 10 MG, Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide 40/10/25 mg