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Progesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.
Mixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%, Minoxidil 7% / Progesterone 0.1%Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigational[L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic
Synonyms: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurineCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesLevofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].
Mixtures: TRILEVO 500 MG+30 MG+ 1000 MG TEDAVİ PAKETİCategories: MATE 2 Inhibitors, Heterocyclic Compounds, 2-RingAtracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnCategories: Heterocyclic Compounds, 2-RingProducts: TRACRİUM 25 MG/2.5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, NEUCURIUM 25 MG/2.5 ML IV INFUZYON VE ENJEKSIYON ICIN COZELTI ICEREN AMPUL, 5 ADETPseudoephedrine
go.drugbank.com/drugs/DB00852Approved[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. … Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.
Mixtures: Zodryl DEC 25, Zodryl DAC 25Categories: Adrenergic alpha-2 Receptor Agonists, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesMagnesium salicylate
go.drugbank.com/drugs/DB01397ApprovedThough the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate … Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations.
Categories: Non COX-2 selective NSAIDSProducts: Back-ese M Tablets 325 mg, Back-ese M Tab 325mgAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalMore recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate … (NMDA) receptor,[A18263] indicating a role for the glutamatergic system in the pathophysiology of ADHD.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: ATTENTHO®25 MG CAPSULAS, ACEPTOL ® 25 MG CAPSULASIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Synonyms: (±)-2-(p-isobutylphenyl)propionic acid, 2-(4-isobutylphenyl)propanoic acidInternational brands: Act-3, Alges-XParoxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigational[L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidineAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalFDA approved January 25, 2013. … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates