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Flotufolastat F-18
go.drugbank.com/drugs/DB17851ApprovedInvestigationalFlotufolastat F-18 (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane antigen (PSMA). In patients with recurrent prostate cancer that require localized treatment, the use of 18F-labeled ligands for posi...
Fexinidazole
go.drugbank.com/drugs/DB12265Approved[A237550, A237560] Fexinidazole, which was originally developed in the 1970s/80s by Hoechst AG and subsequently rediscovered through the Drugs for Neglected Diseases Initiative (DNDi) in 2005, is the first
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesATB-346
go.drugbank.com/drugs/DB15377InvestigationalATB-346 is under investigation in clinical trial NCT03220633 (Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects).
Naveglitazar
go.drugbank.com/drugs/DB12662InvestigationalNaveglitazar has been used in trials studying the treatment of Diabetes Mellitus, Non-Insulin-Dependent.
Categories: PPAR gamma, agonistsSabiporide
go.drugbank.com/drugs/DB21244ExperimentalThe usage of the INN stem '-poride' in the name indicates that Sabiporide is a Na+/H+ antiport inhibitor. Sabiporide has a monoisotopic molecular weight of 408.15 Da.
LGD-1550
go.drugbank.com/drugs/DB05785ExperimentalLGD-1550 is an orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities.
Chlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: Nu-chlorax Capsules USPCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalThe clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, breast cancer and skin conditions such as eczema and psoriasis are being investigated in clinical trials
Bremelanotide
go.drugbank.com/drugs/DB11653Approved[L9635] Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141.
Dipivefrin
go.drugbank.com/drugs/DB00449ApprovedWithdrawnDipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).