Search
Flupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is approved for use in Canada and other countries around the world, but not in the US. … [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitorsProducts: Fluanxol Depot 2% -liq Im 20mg/ml, FLUANXOL DEPOT 20MG/ML IM ENJ. SOLUSYON, 1 ADETDoravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigationalDoravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines. … [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic
Categories: Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor, Non-Nucleoside Reverse Transcriptase InhibitorsCapmatinib
go.drugbank.com/drugs/DB11791ApprovedInvestigational[L13347] The presence of the mutation must be confirmed by an FDA-approved test, such as the FoundationOne CDx assay (manufactured by Foundation Medicine, Inc.), which was approved by the FDA on the same … [L13347] Capmatinib was approved by Health Canada on June 8, 2022.[L42015]
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it
Mixtures: EUSAPRIM K SUS F KDR, TRIMETROPINA SULFA F MKCategories: MATE 1 Inhibitors, MATE 1 SubstratesNF-kappa-B inhibitor alpha
go.drugbank.com/bio_entities/BE0003469TargetHumansInhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimu...
Synonyms: I-kappa-B-alphaCardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-13:0)
smpdb.ca/view/SMP0051177DiseaseBTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-14:0)
smpdb.ca/view/SMP0051178DiseaseBTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-18:0)
smpdb.ca/view/SMP0051182DiseaseBTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.
Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-13:0/i-12:0)
smpdb.ca/view/SMP0051194DiseaseBTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.