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Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigationalIloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties.
Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acidProducts: İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL, İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPULAmifostine
go.drugbank.com/drugs/DB01143ApprovedInvestigationalA phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET, Ethyol - Pws IV 500mg/vialEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedin potency and in estrogenic effects. … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary hormone from estradiol to estrone) is associated with a number of symptoms associated with this reduction
Mixtures: AI PROFAMILIA, CYCLO PROGYNOVA N 2MG/0.15Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalThe injectable intravenous formulation of peramivir was approved by the FDA in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B.
Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (5 Adet)Paricalcitol
go.drugbank.com/drugs/DB00910ApprovedInvestigationalParicalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. … Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 19-Nor-1alpha,25-dihydroxyvitamin D2Generalized joint pain
go.drugbank.com/conditions/DBCOND0093852Drugs: Methyl nicotinateSynonyms: Pain in joint, Ache in jointNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression in opioid overdose. … [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use.
Mixtures: TILIDIN HEXAL COMP D-PUMPE, TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substratesCorticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedCorticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: Acthar Gel Hp Inj 40unit/ml, Acthar Powder Inj 40unit/vialOxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigational[A215542] Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. … [L15057] In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq) in adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment
Synonyms: 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol, 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazolineInternational brands: Genasal Nasal Spray Up to 12 Hour Relief