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Lenacapavir

[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral … HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens

Streptomycin

Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s. … adjunctive treatment in cases of multi-drug resistant tuberculosis.

Podophyllin

Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase. … Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum emodi_, which contains numerous compounds, amongst which is podophyllin (as well as the drug

Enzacamene

It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.

Donidalorsen

[L53788] Donidalorsen was approved by the FDA in August 2025 for prophylactic use to prevent HAE attacks.[L53783,L53788] It is the first RNA-targeted therapy approved for HAE.[L53783] … Hereditary angioedema (HAE) is a rare genetic disease characterized by recurrent episodes of severe swelling induced by excessive production of bradykinin.

Carbidopa

therapy developed by Mayne Pharma in 1992. … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.

Tetryzoline

[L32584, L32589, L32594] It is also used in combination with other drug classes, such as antihistamines, corticosteroids, and glucocorticoids in other countries. … Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, Visine.

Ferric chloride

Eliglustat

[L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease. … In patients with Gaucher disease, the accumulation of glucosylceramide leads to the formation of Gaucher cells that infiltrate the liver, spleen, bone marrow and other organs.

Mequinol

Mequinol is a phenol used in various applications. … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.