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Sparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigationalSparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub … [A257330,L45300] Sparsentan is first in its class and orally active, and was created by merging the structural elements of [irbesartan], an AT<sub>1</sub>R antagonist, and biphenylsulfonamide, an ET<sub
Levodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Products: ALIVTUS® 60MG/10ML. SOLUCION ORAL, TOUSSER 30MG/5ML ŞURUPAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedIt is also used as a coagulant in the water purification process. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.
Products: Avon Roll-ON Lot Inseparable for Her 17.5%, Arrid Ext Dry Unscent Spray Aer 10%Nonivamide
go.drugbank.com/drugs/DB11324ApprovedIt is an alkaloid from the Capsicum species. … Nonivamide has also been studied for its anti-inflammatory properties, as well as in fat loss therapies and has demonstrated promising results [L2643], [A32888], [A32886], [A32884].
Mixtures: Hot Pap CataplasmaPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalIt is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. … It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast [A32838].
Mixtures: Wet Wipes, Wet WipesProducts: DISINFECT Wet WIPESHelium
go.drugbank.com/drugs/DB09155ApprovedInvestigationalVet approvedIt is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table. … It is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of the patient.
Mixtures: COMPRESSED Gas, N.O.S., Helium-oxygen Mix GasPheniramine
go.drugbank.com/drugs/DB01620Approved[A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. … Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine].
Mixtures: Rhume Et De LA Grippe (extra-fort), OCTILIA ALLERGIA E INFIAMMAZIONECategories: Antihistamines, Anesthetics, Etc.Octasulfur
go.drugbank.com/drugs/DB09353ApprovedIt has been also used for acne. … After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli.
Mixtures: Sulfatol 10-4 Cleansing pads, Avar Cleansing PadsProducts: Derma E Acne Clarifying Mask, Get Clarity Foaming Acne CleanserBarbexaclone
go.drugbank.com/drugs/DB09001ExperimentalBarbexaclone exists in 25mg and 100mg tablets. 100mg of barbexaclone is equivalent to 60mg of phenobarbital. … Despite the lack of controlled trials, barbexaclone was used widely in Turkey until it was discontinued in 2009.
Daraxonrasib
go.drugbank.com/drugs/DB22308ApprovedInvestigational[L64039,L64041] Because it targets a broad range of RAS genotypes, it treats tumors with or without an identified RAS mutation and does not require a companion diagnostic test. … [L64039] It is a RAS(ON) tri-complex inhibitor that binds cyclophilin A and targets the active, GTP-bound ("ON") state of RAS, suppressing signaling of both wild-type and mutant RAS across the most common
Categories: RAS GTPase Inhibitors