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Flibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalin the brain as well as an effect on increasing norepinephrine and dopamine neurotransmitters. … Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015.
Mepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThe pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, Nucala 100mg/ml Solution for Injection in pre-filled pen (Autoinjector)Choline
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Mixtures: Doctor's Choice Brand for Men, Multivitamins and Minerals for MenCategories: Vitamin B ComplexAprocitentan
go.drugbank.com/drugs/DB15059ApprovedInvestigational[A263386,L50261] Aprocitentan was approved by the FDA in March 2024 for the treatment of hypertension in patients inadequately controlled with standard therapy. … [L50261] It was the first antihypertensive employing a novel mechanism to be approved in almost 40 years.[L50261]
Influenza A virus A/Michigan/45/2015 X-275 (H1N1) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14458ApprovedInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: SKYCellflu Trivalent Solution for Injection in Prefilled Syringe 0.5ml, SKYCellflu Trivalent Solution for Injection in Prefilled Syringe 0.25mlLofexidine
go.drugbank.com/drugs/DB04948ApprovedInvestigationalLofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersCoagulation factor VII human
go.drugbank.com/drugs/DB13150ApprovedInvestigationalCoagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Mixtures: UMAN COMPLEX, UMAN COMPLEXCategories: coagulation factor IX, II, VII and X in combinationAspergillus flavus
go.drugbank.com/drugs/DB10694ApprovedAspergillus flavus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixturePoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedComposed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons. … P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217].
Categories: Compounds used in a research, industrial, or household settingSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalMost recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953] … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.