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Displaying results 131 - 140 of 1717 in total
  1. Drug

    Ensovibep

    go.drugbank.com/drugs/DB19078
    Investigational

    Ensovibep is under investigation in clinical trial NCT04501978 (ACTIV-3: Therapeutics for Inpatients With COVID-19).

    Categories: Proteins, Recombinant ProteinsSynonyms: Designed ankyrin repeat protein (synthetic bivalent human albumin-binding) fusion protein with designed ankyrin repeat protein (synthetic trivalent severe acute respiratory syndrome coronavirus 2 spike
  2. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.

    Synonyms: Human somatomedin C, VEXXON-IGF-1Categories: Proteins, Blood Proteins
  3. Drug

    SM-1997

    go.drugbank.com/drugs/DB18670
    Experimental

    SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, amino acids, peptides, nucleosides, and nucleotides.

    Synonyms: Solution of protein-free hemodialysate of calf blood
  4. Drug

    Cardiotrophin 1

    go.drugbank.com/drugs/DB18399
    Investigational

    Synonyms: Protein cardiotrophin (human isoform 1), CT-1Categories: Proteins, Amino Acids, Peptides, and Proteins
  5. Drug

    Vorapaxar

    go.drugbank.com/drugs/DB09030
    Approved

    Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c]furan-6-yl]carbamate d'éthyle, Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester
  6. Drug

    Englumafusp alfa

    go.drugbank.com/drugs/DB19341
    Investigational

    and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma). … Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab

    Synonyms: 71-248-4-1BB ligand (human precursor) fusion protein with peptide linker (GGGGS)2 fusion protein with 71-248-4-1BB ligand (human precursor) peptide linker (GGGGS)2 fusion protein with human κ-chain C region, fusion protein with immunoglobulin G1 [497-ala
  7. Drug

    RBIO-101

    go.drugbank.com/drugs/DB18425
    Experimental

    RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.

    Synonyms: recombinant adeno-associated virus vector encoding human CYP4V2 protein
  8. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. … As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

    Synonyms: DNA vaccine expressing SARS-CoV-2 S-protein antigen
  9. Drug

    Efprezimod alfa

    go.drugbank.com/drugs/DB16448
    Investigational

    CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.

    Synonyms: Human CD24 and human IgG Fc Fusion Protein
  10. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Categories: Proteins, Amino Acids, Peptides, and ProteinsSynonyms: paclitaxel protein-bound particles, Paclitaxel protein-bound particles for injection suspension