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Protein C

go.drugbank.com/drugs/DB11312
ApprovedInvestigational

Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on th...

  1. Drug

    Drotrecogin alfa

    go.drugbank.com/drugs/DB00055
    ApprovedWithdrawn

    Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond.

    Categories: Recombinant Activated Protein C, ProteinsSynonyms: Activated protein C, Recombinant human activated protein C (rH-APC)
  2. Drug

    Protein S human

    go.drugbank.com/drugs/DB13149
    ApprovedInvestigational

    Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561]. It serves as a negative feedback mechanism in the coagulation cascade.

    Mixtures: Beriplex P/n 500, Beriplex P/n 1000Categories: Proteins, Blood Proteins
  3. Drug

    Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen

    go.drugbank.com/drugs/DB14428
    ApprovedInvestigational

    Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

    Mixtures: MENVEO®, MENVEO®Synonyms: Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen
  4. Drug

    Vespula vulgaris venom protein

    go.drugbank.com/drugs/DB11033
    Approved

    Vespula vulgaris venom protein is an extract of Vespula vulgaris venom. Vespula vulgaris venom protein is used in allergenic testing.

    Mixtures: Mixed Vespid Venom Protein Inj, Venomil Wasp Venom Protein (12mcg)Synonyms: common wasp venom protein, Yellow jacket venom protein
  5. Drug

    Polistes exclamans venom protein

    go.drugbank.com/drugs/DB11028
    Approved

    Polistes exclamans venom protein is an extract of Polistes exclamans venom. Polistes exclamans venom protein is used in allergenic testing.

    Synonyms: common paper wasp venom protein, Polistes exclamans venom proteinProducts: Pharmalgen Wasp Venom Protein
  6. Drug

    Corynebacterium diphtheriae CRM197 protein

    go.drugbank.com/drugs/DB16712
    ApprovedInvestigational

    Synonyms: Diphtheria CRM197 protein, Corynebacterium diphtheriae CRM-197 proteinCategories: Proteins, Amino Acids, Peptides, and Proteins
  7. Drug

    Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen

    go.drugbank.com/drugs/DB10799
    ApprovedInvestigational

    The vaccine contains *N. meningitis* serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are extracted from Corynebacterium diphtheriae … meningitidis* serogroup c.

    Synonyms: Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine, Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
  8. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Mito-C, Mitocin-C
  9. Drug

    Equine Botulinum Neurotoxin C Immune FAB2

    go.drugbank.com/drugs/DB13898
    Approved

    Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in adults and pediatric patients.

    Synonyms: Botulinum Neurotoxin C immune FAB2 (equine), BOTULINUM NEUROTOXIN C IMMUNE FAB2, EQUINE