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Ocrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigationalThe addition of hyaluronidase allows for subcutaneous injection, which is a method often preferable for patients and provides an alternative means of administration for sites lacking IV infrastructure, … Developed by Genentech/Roche, ocrelizumab was approved by the FDA in March 2017 under the market name Ocrevus for intravenous injection.
Products: OCREVUS 300mg/10mL Concentrate for Solution for Infusion, Ocrevus 920mg/23ml Solution for InjectionGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigational[A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive treatment of migraine and the treatment of episodic cluster headache. … [A33105] Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsProducts: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, Pontevia 120 mg solution for injection in pre-filled penCeftaroline fosamil
go.drugbank.com/drugs/DB06590ApprovedInvestigationalCeftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Zinforo Powder for Concentrate for Solution for Infusion 600mg/vial, Zinforo 600mg Powder for Concentrate for Solution for InfusionRanibizumab
go.drugbank.com/drugs/DB01270ApprovedInvestigationalIn order to improve drug delivery to the target organ, ranibizumab is available for intravitreal use. … ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and used in the off-label treatment of neovascular age-related macular degeneration for
Products: Lucentis 10mg/ml Solution for Injection, ACCENTRIX 10MG/ML SOLUTION FOR INJECTIONInclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigational[A225953,A225958] On December 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and only approved siRNA for the treatment of adults with primary hypercholesterolemia … [L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled SyringeCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalIts side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Mixtures: Procytox for Injection 2000mg Pws IVProducts: Cytoxan Pws for Inj 1000mg/vial, Cytoxan Pws for Inj 2000mg/vialAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529].
Products: ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONDaratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs. … [L13290,L13296] A subcutaneous formulation of daratumumab co-formulated with hyaluronidase-fihj is also approved for the treatment of adults with multiple myeloma.
Products: DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5MLIndocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalIndocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. … Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
Products: Spy Agent Green Kit for Spy Elite, Spy Agent Green Kit for Spy-phiMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. … [A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases.
Products: CELLCEPT FOR I.V. INFUSION 500 mg/vial, Mycophenolate Mofetil for Injection USP