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Polyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a rati...
Mixtures: Gavilyte-NCategories: P-glycoprotein inhibitorsPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Mixtures: BIPRETERAX N 5MG/1.25MG, BIPRETERAX N 5MG/1.25MGProducts: Nb-perindopril, PERINDOPRIL ERB 1A PH 4MGCaptopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalCaptopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the r...
Categories: P-glycoprotein inhibitorsProducts: Nu-capto Tab 50mg, Nu-capto Tab 25mgLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigational[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no potential to produce, or be subject to, pharmacokinetic interactions[L8606,L8600,L8615] - these characteristics
Categories: P-glycoprotein substratesProducts: KEPPRA 100MG/ML 10MLDOS PI, KEPPRA 100MG/ML 10ML DOS PFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigationalFenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. Fenofibrate was granted FDA approval on 31 December 1993.
Synonyms: Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: Super Daily No 2, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHAProducts: NP Ferrous Fumarate 200mg TabletTrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigationalTrihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders. Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. Trihe...
Products: Nu-trihexyphenidylFlutamide
go.drugbank.com/drugs/DB00499ApprovedInvestigationalAn antiandrogen with about the same potency as cyproterone in rodent and canine species.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nu-flutamide TabletsMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these form...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nu-metoprolol, Nu-metoprolol SRTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is norm...
Mixtures: Throwers Pbc No. 1Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates