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Dronedarone
go.drugbank.com/drugs/DB04855ApprovedInvestigational[A34604,T28] Additionally, the methyl sulfonyl group in its structure renders dronedarone to be more lipophilic with a shorter half-life than amiodarone. … [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009.
Synonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamideCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index2'-fluoro-5-ethylarabinosyluracil
go.drugbank.com/drugs/DB13030Investigational2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma
Synonyms: 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracilCategories: Heterocyclic Compounds, 1-RingZalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnThis modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one, 2',3'-Dideoxycytidine2'-Deoxycytidine 5'-triphosphate
go.drugbank.com/drugs/DB03258ExperimentalSynonyms: 2'-Deoxycytidine 5'-triphosphate, 2'-Deoxycytidine-5'-TriphosphateCategories: Heterocyclic Compounds, 1-Ring5-(2-chlorophenyl)furan-2-carbohydrazide
go.drugbank.com/drugs/DB08757ExperimentalSynonyms: 5-(2-chlorophenyl)furan-2-carbohydrazide5-(2-CHLOROBENZYL)-2-FUROIC ACID
go.drugbank.com/drugs/DB07308ExperimentalSynonyms: 5-(2-CHLOROBENZYL)-2-FUROIC ACID5-(2-METHOXYPHENYL)-2-FUROIC ACID
go.drugbank.com/drugs/DB07407ExperimentalSynonyms: 5-(2-METHOXYPHENYL)-2-FUROIC ACID5-(2-NITROPHENYL)-2-FUROIC ACID
go.drugbank.com/drugs/DB07408ExperimentalSynonyms: 5-(2-NITROPHENYL)-2-FUROIC ACIDCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigationalCladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Categories: 2-Chloroadenosine, Heterocyclic Compounds, 2-RingSynonyms: 2-chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine, (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol