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Displaying results 131 - 140 of 157601 in total
  1. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.

    Mixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTACategories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor Agonists
  2. Drug

    Boldenone undecylenate

    go.drugbank.com/drugs/DB14639
    ExperimentalIllicitVet approved

    Synonyms: 17beta-Hydroxyandrosta-1,4-dien-3-one 10-undecenoate, Boldenone 10-undecenoate
  3. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Another benefit latanoprost is that it can be administered once a day.[A184490] … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998.

    Mixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenCategories: Prostaglandins F, Synthetic, Compounds used in a research, industrial, or household setting
  4. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. … It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridine
  5. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.

    Mixtures: ILTUXAM ® 20 MG - 10 MG, SEVIKAR HCT 40 mg/10 mg/25 mg FilmtablettenCategories: Angiotensin 2 Receptor Blocker
  6. Drug

    Trimethoprim

    go.drugbank.com/drugs/DB00440
    ApprovedInvestigationalVet approved

    Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it … [L11893,L11830] It is structurally and chemically related to [pyrimethamine], another antifolate antimicrobial used in the treatment of plasmodial infections.[T707]

    Mixtures: SEPTRIN IV 5 ML 10 AMPUL, METOPRIM 200 MG + 40 MG/5 ML SUSPANSIYON, 100 MLCategories: MATE 1 Inhibitors, MATE 1 Substrates
  7. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough.

    Mixtures: LOSARBAY®- H COMPRIMIDOS RECUBIERTOS 50 MG / 12. 5 MG, ARAMAX ® 5/50 MG TABLETASCategories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor Blockers
  8. Drug

    Tolcapone

    go.drugbank.com/drugs/DB00323
    ApprovedInvestigationalWithdrawn

    It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenone
  9. Drug

    Eleuthero

    go.drugbank.com/drugs/DB14303
    ApprovedInvestigational

    Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Et Maxim.) Maxim. Root, Acanthopanacis Senticosi Radix Et Rhizoma Seu Caulis
  10. Drug

    Idoxuridine

    go.drugbank.com/drugs/DB00249
    ApprovedWithdrawn

    An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil