Search
Ranolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigationalChronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of t...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Mar-ranolazine XREdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalEdoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. … is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE
Categories: P-glycoprotein substrates, Factor Xa InhibitorsCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigationalCaffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophy...
Mixtures: X RAY DOL®, X RAY DOL®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalvascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SIMVASTATIN Q-PH 10MG FTA, SIMVASTATIN Q-PH 20MG FTALoratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigational[A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: XL-3 DIA, LORACERT- P JARABECategories: P-glycoprotein inhibitors, P-glycoprotein substratesTiamulin
go.drugbank.com/drugs/DB11468ExperimentalVet approvedTiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2E1 InhibitorsProducts: PF TIAMULIN PREMIX 10% W/W POWDER, Biomutin 200 mg/ml Solution for InjectionNimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalIt acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Regental XR, .-0.2mg/mlMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigationalMethotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate i...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidSertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in th...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: XL-3 INFANTIL, SERTRANQUIL TABLETAS X 100 MG.Formoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration
Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates