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Displaying results 1391 - 1400 of 10000 in total
  1. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].

    Mixtures: CİBADREX 10/12,5 MG FİLM TABLET, 28 ADET, CİBADREX 5/6,25 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Simethicone

    go.drugbank.com/drugs/DB09512
    ApprovedInvestigational

    [A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308] … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.

    Mixtures: PANLIPAZ 170/80 MG ENTERİK KAPLI FİLM TABLET, 20 ADET, TRIMEBUTINA 200 MG + SIMETICONA 120 MGCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    SAR443122

    go.drugbank.com/drugs/DB16492
    Investigational

    NCT04469621 was studied in severe COVID-19 patients, while NCT05588843 is currently recruiting participants with ulcerative colitis.

    Categories: Experimental Unapproved Treatments for COVID-19Synonyms: 1H-1,2,4-TRIAZOLE-5-CARBOXAMIDE, 3-(PHENYLMETHYL)-N-((3S)-2,3,4,5-TETRAHYDRO-5-METHYL-4-OXOPYRIDO(3,2-B)(1,4)OXAZEPIN-3-YL)-, 3-(PHENYLMETHYL)-N-((3S)-2,3,4,5-TETRAHYDRO-5-METHYL-4-OXOPYRIDO(3,2-B)(1,4)OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-5-CARBOXAMIDE
  4. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

    Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Vitamin K, Cytochrome P-450 CYP1A2 Inducers
  5. Drug

    Sakuranetin

    go.drugbank.com/drugs/DB08517
    Experimental

    Synonyms: 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-chroman-4-one, (2S)-sakuranetinCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men

    Categories: Prostaglandins E, Prostaglandin E1 AgonistSynonyms: (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, Prostaglandin E1
  7. Drug

    Paritaprevir

    go.drugbank.com/drugs/DB09297
    ApprovedInvestigational

    therapy option when used in combination with other antivirals for genotypes 1a, 1b, and 4[L852]. … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].

    Mixtures: VIEKIRAX 12.5 MG/75 MG/50 MG FILM KAPLI TABLET ,56 TABLETCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  8. Drug

    Hydronidone

    go.drugbank.com/drugs/DB06299
    Investigational

    Hydronidone has antifibrotic activity.

    Synonyms: N-(4-Hydroxyphenyl)-5-methyl-2-pyridoneCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Benzolamide

    go.drugbank.com/drugs/DB07050
    Investigational

    Synonyms: 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamideCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Cloxyquin

    go.drugbank.com/drugs/DB15933
    Experimental

    Synonyms: 5-Chloro-8-hydroxyquinolineCategories: Heterocyclic Compounds, 2-Ring