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Vericiguat
go.drugbank.com/drugs/DB15456ApprovedInvestigational[L31178] Although not the first sGC stimulator to be granted FDA approval ([riociguat] was approved in 2013 for use in pulmonary hypertension),[L3955] vericiguat is unique amongst its peers in that modifications … Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations.
Categories: Vasodilators Used in Cardiac DiseasesPyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalDuring transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine). … This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
Mixtures: L-Methyl-B6-B12, L-Methyl-B6-B12Relebactam
go.drugbank.com/drugs/DB12377ApprovedInvestigationalinfections in adults. … Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam].
Oleic Acid
go.drugbank.com/drugs/DB04224ApprovedInvestigationalVet approvedAn unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.
Mixtures: Borage Oil Capsules, Gla 130 Primrose OilMoxisylyte
go.drugbank.com/drugs/DB09205Approved[T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired the denomination of orphan product by the FDA. … Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist.
Categories: Drugs Used in Erectile DysfunctionAloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalWhile aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products. … It is a perennial succulent xerophyte with elongated leaves that contain a clear gel.
Mixtures: OilLumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigational[A189093] Further, not only is the new antipsychotic selective for dopamine (D2) receptors in the mesolimbic and mesocortical brain regions, but it also has minimal off-target activity. … [A189093] It has a unique receptor binding profile and differs from other antipsychotics in that it modulates glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology
Febuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones … [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout who have an inadequate response or intolerance to [allopurinol
Products: FEBUXOSTAT AL 80MG FTA, FEBUXOSTAT AL 120MG FTAAmisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigational[L32759] It is marketed under the brand name Barhemsys. … In the US, the intravenous formulation of amisulpride is used to treat and prevent postoperative nausea and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of
Products: SOLIAN 100 MG/ML ORAL SOLUSYON, 60 ML, Solian 100 mg/ml TropfenBoric acid
go.drugbank.com/drugs/DB11326ApprovedInvestigationalBoric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and … It is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and candidiasis [A32449].
Categories: Compounds used in a research, industrial, or household setting