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Tebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigationalto be approved by the FDA. … This approval marks the first bispecific T cell engager to be approved by the FDA to treat a solid tumour and being the first and only therapy for the treatment of unresectable or metastatic uveal melanoma
Categories: Bispecific gp100 Peptide-HLA-directed CD3 T Cell EngagerAbciximab
go.drugbank.com/drugs/DB00054ApprovedWithdrawnAbciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules … Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3.
Cetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix does not allow the premature release of these eggs to occur. … When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released.
Products: CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 7 ADETEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. … [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]
Remifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTuroctocog alfa
go.drugbank.com/drugs/DB09109ApprovedTuroctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally … During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification
Products: NOVOEİGHT 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, NOVOEİGHT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETPhosphoric acid
go.drugbank.com/drugs/DB09394ApprovedInvestigationalPhosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Mupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approved[A178531,A178591] Mupirocin is commonly marketed under the brand name Bactroban. … Due to its unique mode of action of inhibiting the activity of bacterial isoleucyl-tRNA synthetase, mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it
Synonyms: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acidInternational brands: T-BactMelphalan
go.drugbank.com/drugs/DB01042ApprovedInvestigational[L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard. … [L47890] It is also used to treat uveal melanoma with unresectable hepatic metastases.[L47895]
Products: ERİOLAN 50 MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET LİYOFİLİZE TOZ İÇEREN FLAKON+1 ADET ÇÖZÜCÜ İÇEREN FLAKONSegesterone acetate
go.drugbank.com/drugs/DB14583ApprovedAccording to the Center for Disease Control, more than 43 million women in the U.S. are at risk of unintended pregnancy, which may be associated with an elevated risk for improper prenatal care, premature … Due to its rapid hepatic metabolism, segesterone acetate must be administered parenterally [A37090].