Search

Displaying results 1411 - 1420 of 10000 in total
  1. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation … Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent

    Synonyms: 3-carboxy-4-hydroxyaniline, 5-ASAProducts: sF Rowasa, PENTASA® ENEMA 1 G
  2. Drug

    CRA-028129

    go.drugbank.com/drugs/DB05951
    Experimental

    CRA-028129 is cathepsin S inhibitor which is under investigation for the treatment of psoriasis.

  3. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    through V<sub>1</sub> and V<sub>2</sub> cellular receptors. … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]

    Products: VASOPRESSIN INJECTION USP 20 u/ml, VASOPRESINA INYECTABLE 20 U/ML USP
  4. Drug

    Maltose

    go.drugbank.com/drugs/DB03323
    Investigational

    A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh&#39;s Chemical Dictionary, 5th ed).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: D-(+)-maltose
  5. Drug

    Methoxyamine

    go.drugbank.com/drugs/DB06328
    Investigational

  6. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L8072] It was developed during World War II as a derivative of [quinacrine] with less severe side effects.

    Synonyms: 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Corticosterone

    go.drugbank.com/drugs/DB04652
    Investigational

    (From Goodman and Gilman&#39;s The Pharmacological Basis of Therapeutics, 8th ed, p1437) … An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: Kendall's compound B, Reichstein's substance H
  8. Drug

    Gatralimab

    go.drugbank.com/drugs/DB16528
    Investigational

    Gatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial

  9. Drug

    Ripertamab

    go.drugbank.com/drugs/DB16314
    Investigational

    Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens ms4a1 (membrane-spanning 4-domains subfamily a member 1, cd20)), chimeric monoclonal antibody, Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma.1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa.-chain, dimer
  10. Drug

    Vigabatrin

    go.drugbank.com/drugs/DB01080
    ApprovedInvestigational

    Although administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active. … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual

    Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 Enzyme InducersSynonyms: 4-Amino-5-hexenoic acid