DB04652InvestigationalSmall molecule
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437).
- Mechanism
- Curator reviewed
Pharmacologically active on 11-beta-hydroxysteroid dehydrogenase 1, Nuclear receptor coactivator 1, and Mineralocorticoid receptor
- Formula / weight
- C21H30O4 · 346.4605 g/mol (avg)
- Also known as
- 17-deoxycortisol · Kendall's compound B · Reichstein's substance H
Resolves to
Structure
InChIKey
OMFXVFTZEKFJBZ-HJTSIMOOSA-NSMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@]([H])(O)C[C@]12C)C(=O)COTransporters
What you can answer from here — as of September 23, 2026
4Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
1TransporterSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Corticosterone, and which of those have an active Phase 3 trial?
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