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Zidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. [PubChem]
Mixtures: LAMIVUDINA E ZIDOVUDINA MYLAN, LAMIVUDINA E ZIDOVUDINA MYLANCategories: Antivirals used in combination for the treatment of HIV infectionsMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalIt also has a number of unique characteristics that have led to its increased use in the last two decades; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids … At higher doses, methadone use can result in respiratory depression, overdose, and death.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigational[L2831] It is also considered as an active ingredient in over-the-counter products.[L1113] … [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.
Mixtures: PEN Prep Plus, Min-tran TabProducts: PEN PrepNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11985] Neomycin sulfate is the most common form for pharmaceutical preparations; because the compound is a complex, the amount of neomycin in products is measured in units. … [L10716] Neomycin is also available in over-the-counter topical products to prevent minor skin infections.
Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticProducts: N-bac creamConestat alfa
go.drugbank.com/drugs/DB09228ApprovedAdditionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. … Intravenous replacement of C1 esterase inhibitor results in reversal of acute symptoms of HAE.
Categories: Drugs Used in Hereditary AngioedemaCeftobiprole
go.drugbank.com/drugs/DB04918ApprovedWithdrawnfor skin and skin structure infections and bacteremia in April 2024. … [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications
Acetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigational(Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.
Mixtures: ICEKING Skin Expert Anti-onychomycosis Gel, AMINOSTERIL N-HEPA 8%Categories: Compounds used in a research, industrial, or household settingPentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnWhen administered, pentastarch remains mainly in the circulatory system and hence, it is considered a plasma expander. … Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation.
Categories: Compounds used in a research, industrial, or household settingPolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPEGs, along with their many nonionic derivatives, are widely utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners. … In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788].
Mixtures: Core Values Eye Drops Dry Eye Relief, Core Values Eye Drops Advanced ReliefCategories: Compounds used in a research, industrial, or household settingSacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigational[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. … [A193671] One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38.