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Nateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the p...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPenfluridol
go.drugbank.com/drugs/DB13791InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigationalTestosterone undecanoate is the ester prodrug of testosterone and has a mid-chain fatty acid at the carbon 17β position. It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. T...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesStanolone acetate
go.drugbank.com/drugs/DB13951ExperimentalStanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.
Categories: P-glycoprotein substratesEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedEstradiol acetate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex h...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesEstradiol dienanthate
go.drugbank.com/drugs/DB13955ApprovedVet approvedWithdrawnEstradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female s...
Categories: Cytochrome P-450 CYP1A1 Substrates, P-glycoprotein substratesFish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalFish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient,...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substratesalpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) s...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates5-methoxy-N,N-dimethyltryptamine
go.drugbank.com/drugs/DB14010IllicitInvestigational5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryp...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesClinafloxacin
go.drugbank.com/drugs/DB14025ExperimentalClinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors