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Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalStructurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine] that has been available clinically since 1920.
Categories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Hydal 1,3 mg Kapseln, Hydal 2,6 mg KapselnTisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationalor after chemotherapy. … [A238914] On September 20, 2021, the FDA granted accelerated approval to tisotumab vedotin for the treatment of recurrent or metastatic cervical cancer in adults in whom the disease progressed during
Lasofoxifene
go.drugbank.com/drugs/DB06202ApprovedInvestigationalWithdrawnIt is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. … Ligand Pharmaceuticals signed a license agreement with Sermonix Pharmaceuticals for the development and commercialization of oral lasofoxifene in the USA.
Categories: Sex Hormones and Modulators of the Genital SystemChlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Categories: combinations of sulfonamidesVorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalpersists, gets worse, or comes back during or after treatment with other medicines. … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease
Products: ZOLINZA®VORINOSTAT 100 MG CAPSULASPatiromer
go.drugbank.com/drugs/DB09263ApprovedInvestigationalEach gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. … Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.
Categories: Compounds used in a research, industrial, or household settingSynonyms: ZG-801Rizatriptan
go.drugbank.com/drugs/DB00953ApprovedInvestigational[L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: RIZATRIPTAN EG, Ag-rizatriptan ODTMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures. … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideSufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigational(AcelRx), was approved on November 2, 2018 [L4717]. … Also known as _Dsuvia_, the sublingual form is used for the management of acute pain in adults that is severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnA barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. … It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure.
Categories: combinations of barbituratesProducts: PENTAL SODYUM 1 G ENJEKTABL SOLÜSYON, 1 ADET, PENTAL SODYUM 0.5 G ENJEKTABL SOLÜSYON, 1 ADET