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CX-046684
go.drugbank.com/drugs/DB19414ApprovedCX-046684 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage KP.2. … It is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.[L40074]
Brentuximab
go.drugbank.com/drugs/DB05471InvestigationalBrentuximab (SGN-30) is an engineered monoclonal antibody (mAb) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of hematologic malignancies as compared … SGN-30 has demonstrated objective antitumor responses as a single agent in phase II clinical trials.
Verapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigational[L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold … greater potency than the R-enantiomer, but is metabolized at a higher rate.
Mixtures: TARKA® SR TABLETAS, TARKA® SR240/4 TABLETAS.Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSecretin human
go.drugbank.com/drugs/DB09532ApprovedInvestigationalAlthough it is a gastrointestinal hormone, secretin is also considered as a neuropeptide hormone since it is also expressed in the central nervous system [A32275]. … Purified synthetic human secretin, also referred to as RG1068, is available as an intravenous injection under the market name ChiRhoStim ® in the U.S..
EVT 201
go.drugbank.com/drugs/DB05721InvestigationalEVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc.
Categories: Heterocyclic Compounds, 2-RingBemotrizinol
go.drugbank.com/drugs/DB11206ApprovedBemotrizinol is commonly marketed as Tinosorb S and Escalol S. … Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays.
Mixtures: ELROEL Pang Pang Big Sun Cushion S7, ELROEL Pang Pang Mini Sun Cushion S7Categories: Heterocyclic Compounds, 1-RingCositecan
go.drugbank.com/drugs/DB05806InvestigationalCositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Isatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigationalIsatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.
Products: SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SARCLİSA 500 MG/25 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETOxybenzone
go.drugbank.com/drugs/DB01428ApprovedIt is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. … Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents.
Synonyms: 2-Benzoyl-5-methoxyphenol, 2-Hydroxy-4-methoxybenzophenoneMixtures: Defense Zone C/S Broad Spectrum SPF 30, Defense Zone Kids C/S Broad Spectrum SPF 50Biricodar
go.drugbank.com/drugs/DB04851InvestigationalThe pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring