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Clesrovimab
go.drugbank.com/drugs/DB18877Approved[A273953,A273978] Clesrovimab-cfor was approved by the US FDA in June 2025 for use in infants prior to or during their first RSV season.[L53228,L53233] … [L53233] As there are no RSV vaccines approved for infant patients, nor are vaccines immediately effective in this population, clesrovimab and similar monoclonal antibodies like [nirsevimab] are designed
Metandienone
go.drugbank.com/drugs/DB13586ApprovedWithdrawnIt was introduced to the market in the 1960s but later discontinued and withdrawn from the market. … [A254432] In the US, metandienone is a controlled substance under the Controlled Substances Act.[L44057]
Categories: Androgens for Topical Use, Anabolic Agents for Systemic UseConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigational[T475] The conjugated estrogen mixture was approved for marketing in US in 1942 based on the efficacy against certain conditions. … The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material.
Norethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigational[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol … [L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use
Categories: Hormonal Contraceptives for Systemic UseSynonyms: 19-nor-ethindrone, 19-nor-17α-ethynyltestosteroneCholine
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Mixtures: Palm Spring's PM Form Tab, For-2Ornidazole
go.drugbank.com/drugs/DB13026InvestigationalOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: ORNIDONE FORT 500 MG FILM TABLET, 10 ADET, ORNISID FORT 500 MG FİLM KAPLI TABLET, 10 ADETDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigationalIt was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation.[L41955] It was also used for metastatic non-small cell lung cancer with the same mutation. … [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955]
Ceftolozane
go.drugbank.com/drugs/DB09050ApprovedInvestigational[L6685] It was approved by the FDA in 2014 for use in combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. … [A179422] Most recently, in June 2019, ceftolozane-tazobactam was approved for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.
Mixtures: ZERBAXA POWDER FOR SOLUTION FOR INJECTION 1G/0.5G, Zerbaxa 1.5g powder for solution for injectionEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalThe intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to … [L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression.
Categories: Antidepressive Agents Indicated for DepressionCrovalimab
go.drugbank.com/drugs/DB16128ApprovedInvestigational[L50908] First developed by Chugai Pharmaceutical, in collaboration with Roche, crovalimab was first approved in China in February 2024 for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). … [A263958] It soon gained its approval in Japan in the next month,[A263958] and in the USA in June of the same year.