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Lefamulin
go.drugbank.com/drugs/DB12825ApprovedA pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. … Lefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCebranopadol
go.drugbank.com/drugs/DB12830InvestigationalCebranopadol has been used in trials studying the treatment of Pain, Neoplasms, and Chronic Pain.
Categories: Heterocyclic Compounds, 2-RingOlipudase alfa
go.drugbank.com/drugs/DB12835ApprovedInvestigational[L42740] ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid sphingomyelinase and the abnormal accumulation of the primary ASM substrate, sphingomyelin
Pirnabine
go.drugbank.com/drugs/DB12840InvestigationalPirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation.
Categories: Guanylyl Cyclase C AgonistsPyroxamide
go.drugbank.com/drugs/DB12847InvestigationalPyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Categories: Heterocyclic Compounds, 1-RingPF-04217903
go.drugbank.com/drugs/DB12848InvestigationalPF-04217903 has been used in trials studying the treatment of Neoplasms.
Categories: Heterocyclic Compounds, 1-RingNVP-LEQ-506
go.drugbank.com/drugs/DB12857InvestigationalLEQ506 has been used in trials studying the treatment of Advanced Solid Tumors, Recurrent or Refractory Medulloblastoma, and Locally Advanced or Metastatic Basal Cell Carcinoma.
Categories: Heterocyclic Compounds, 1-RingPradigastat
go.drugbank.com/drugs/DB12866InvestigationalPradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).
Categories: Heterocyclic Compounds, 1-RingButhionine sulfoximine
go.drugbank.com/drugs/DB12870InvestigationalButhionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Synonyms: Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, DL-buthionine-(S,R)-sulfoximineCategories: Compounds used in a research, industrial, or household settingOmigapil
go.drugbank.com/drugs/DB12879InvestigationalOmigapil has been used in trials studying the treatment of Congenital Muscular Dystrophy.
Categories: Heterocyclic Compounds, 1-Ring