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Pantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedPantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. … Pantothenic acid is an ingredient in some hair and skin care products.
Mixtures: Ribotin-E, Multi II IV Vi TabCategories: Vitamin B ComplexInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … These molecules have structural similarities to glucose and are involved in cellular signaling.
Mixtures: Multi II IV Vi Tab, Multi Plex I - TabCategories: Vitamin B ComplexSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].
Mixtures: SITAGLIPTIN E METFORMINA GALENICUM, SITAGLIPTIN E METFORMINA GALENICUMCategories: Drugs Used in Diabetes, DPP-IV InhibitorsPitolisant
go.drugbank.com/drugs/DB11642ApprovedInvestigational[A32024] The therapeutic effectiveness of pitolisant was comparable to that of [modafinil]. … In a European clinical trial of adult patients with narcolepsy, there was a reduction in the Epworth Sleepiness Scale (ESS) score from pitolisant therapy compared to placebo.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 InducersMeloxicam NSAID Action Pathway
smpdb.ca/view/SMP0124609Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase. … Because meloxicam decreases PGE2 in the CNS, it has an antipyretic effect. Antipyretic effects result in increased peripheral blood flow, vasodilation, and subsequent heat dissipation.
Enzymes: Prostaglandin E synthaseAcetaminophen Action Pathway (New)
smpdb.ca/view/SMP0122823Drug actionProstaglandin H2 leads to the formation of thromboxane A2 (via thromboxane-A synthase), prostacyclin (via prostacyclin synthase) and prostaglandin E2 (via prostaglandin E synthase). … Its exact mechanism is unknown but it is thought to target the cyclooxygenase pathway in the CNS (brain).
Enzymes: Prostaglandin E synthaseValdecoxib Action Pathway (New)
smpdb.ca/view/SMP0124454Drug actionIt targets the prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. … The cyclooxygenase pathway begins in the cytosol with phospholipids being converted into arachidonic acid by the action of phospholipase A2.
Enzymes: Prostaglandin E synthaseCarprofen NSAID Action Pathway
smpdb.ca/view/SMP0124580Drug actionIt is no longer used in the clinical setting, but is approved for use in dogs. … Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseFenoprofen Anti-inflammatory Action Pathway
smpdb.ca/view/SMP0124610Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Because fenoprofen decreases PGE2 in the CNS, it has an antipyretic effect. Antipyretic effects results in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation.
Enzymes: Prostaglandin E synthaseIbuprofen NSAID Action Pathway
smpdb.ca/view/SMP0124611Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase. … Cytokines are produced in the central nervous system (CNS) during an inflammatory response.
Enzymes: Prostaglandin E synthase