Fenoprofen

DB00573ApprovedSmall moleculeAnti-Inflammatory Agents, Non-Steroidal

Fenoprofen is an anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins.

Chemical structure of Fenoprofen
Mechanism
Curator reviewed
Primary indication
For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis.Curator reviewed · 4 structured indications
Formula / weight
C15H14O3 · 242.2699 g/mol (avg)
First approval
Canada, 1975 · United States, 2006
Code names
69323 · LILLY-53858
Brand names
  • Fenopron
  • Fenortho
  • Nalfon

Resolves to

Compound
UNIIRA33EAC7KYCAS29679-58-1ChEMBLCHEMBL1297ChEBI5004PubChem3342KEGGD00968
Clinical / RWD
RxNorm4331ATCM01AE04PharmGKBPA449597
Structure
InChIKeyRDJGLLICXDHJDY-UHFFFAOYSA-NSMILESCC(C(O)=O)C1=CC(OC2=CC=CC=C2)=CC=C1
Targets
P35354PTGS2P23219PTGS1Q07869PPARAP37231PPARG

What you can answer from here — as of September 13, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,665Drug interactionsStructured to mechanism, not free text
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4Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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50Marketed productsAcross 3 countries and 26 labellers
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1ATC codeIncluding every combination product, plus 23 drug categories
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14+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Fenoprofen, and which of those have an active Phase 3 trial?

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