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Displaying results 1481 - 1490 of 10000 in total
  1. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. … TCAs also block histamine-H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred

    Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
  2. Drug

    Golcadomide

    go.drugbank.com/drugs/DB18115
    Investigational

    Synonyms: 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl} phenyl) methyl]amino}-1H-isoindole-1,3(2H)-dione
  3. Drug

    Isoliquiritigenin

    go.drugbank.com/drugs/DB03285
    Experimental

    Isoliquiritigenin is a precursor to several flavonones in many plants.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A InhibitorsSynonyms: (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one, (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone
  4. Drug

    Eliglustat

    go.drugbank.com/drugs/DB09039
    ApprovedInvestigational

    Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease. … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide
  5. Drug

    3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE

    go.drugbank.com/drugs/DB07959
    Experimental

    Synonyms: 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
  6. Drug

    (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID

    go.drugbank.com/drugs/DB07979
    Experimental

    Synonyms: (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
  7. Drug

    Guanosine 5'-diphosphate 2':3'-cyclic monophosphate

    go.drugbank.com/drugs/DB02836
    Experimental

    Synonyms: Guanosine 5'-diphosphate 2':3'-cyclic monophosphate
  8. Drug

    Cmp-2-Keto-3-Deoxy-Octulosonic Acid

    go.drugbank.com/drugs/DB04482
    Experimental

    Synonyms: Cmp-2-Keto-3-Deoxy-Octulosonic Acid
  9. Drug

    Tolazamide

    go.drugbank.com/drugs/DB00839
    Approved

    A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide, 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea
  10. Drug

    5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide

    go.drugbank.com/drugs/DB07875
    Experimental

    Synonyms: 5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide