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Osugacestat
go.drugbank.com/drugs/DB12006InvestigationalOsugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide, Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluorophenyl)-, (2R,3S)-Prexasertib
go.drugbank.com/drugs/DB12008InvestigationalPrexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Categories: Heterocyclic Compounds, 1-RingPonesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1-phosphate receptor 1 than [fingolimod]. … Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing forms of multiple sclerosis in adults.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalBenralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®Ammonio methacrylate copolymer type A
go.drugbank.com/drugs/DB12031InvestigationalAmmonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.
Synonyms: Ammonio methacrylate copolymer type AInternational brands: Eudragit RL 30 DVedroprevir
go.drugbank.com/drugs/DB12037InvestigationalVedroprevir has been investigated for the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 2-RingEpicatechin
go.drugbank.com/drugs/DB12039InvestigationalEpicatechin has been used in trials studying the treatment of Pre-diabetes.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingIbodutant
go.drugbank.com/drugs/DB12042InvestigationalIbodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea.
Categories: Heterocyclic Compounds, 1-Ring, Receptors, Neurokinin-2, antagonists & inhibitorsSetrobuvir
go.drugbank.com/drugs/DB12051InvestigationalSetrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 2-RingIcariin
go.drugbank.com/drugs/DB12052InvestigationalIcariin has been investigated for the basic science of the Pharmacokinetic Profile of Icariin in Humans.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring