Setrobuvir

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DB12051InvestigationalSmall molecule

Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.

Mechanism: Pharmacologically active on RNA-directed RNA polymerase
Curator reviewed
Formula / weight: C₂₅H₂₅FN₄O₆S₂ · 560.62 g/mol (avg)
Code names: ANA-598 · RO-5466731

Resolves to

Compound

UNIIT5B2GI8F84CAS1071517-39-9ChEMBLCHEMBL1076263PubChem126843190

Structure

InChIKeyDEKOYVOWOVJMPM-RLHIPHHXSA-NSMILESCS(=O)(=O)NC1=CC=C2NC(=NS(=O)(=O)C2=C1)C1=C(O)[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2N(CC2=CC=C(F)C=C2)C1=O

Targets

O39930NS5bP26664Genome polyprotein

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

115Drug interactionsStructured to mechanism, not free text

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Setrobuvir, and which of those have an active Phase 3 trial?

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