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Lenograstim
go.drugbank.com/drugs/DB13144ApprovedWithdrawnLenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Synonyms: G-CSF (CHO cell derived), Glycosylated recombinant G-CSFProducts: GRANOCYTE 34 MU ENJEKSİYONLUK/İNFÜZYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity
Mixtures: TROK G® CREMA, B-TASONE-G CREAMCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexBismuth subgallate
go.drugbank.com/drugs/DB13909ApprovedIt is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. … Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight.
Mixtures: KORTOS KREM, 30 GVorapaxar
go.drugbank.com/drugs/DB09030ApprovedBy inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation. … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history
Categories: Protease-activated Receptor-1 Antagonist, Protease-activated Receptor-1 AntagonistsSynonyms: [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c]furan-6-yl]carbamate d'éthyle, Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl esterAnacaulase
go.drugbank.com/drugs/DB17449ApprovedInvestigationalAnacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (_Ananas comosus_ [L.] Merr.). … and the N-linked glycan of stem bromelain and small molecule metabolites.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsThiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalThiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_. … It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663]
Mixtures: VETEXINE COMBO %1/%0.25 JEL, 50 G, MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 GSynonyms: Thiocolchicine 2-glucoside analogOrnithine Transcarbamylase Deficiency
go.drugbank.com/conditions/DBCOND0037181Drugs: Phenylbutyric acidSynonyms: OTC-gene related ornithine carbamoyltransferase deficiencyFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold.
Products: ARIXTRA ® 10MG /0.8 ML, ARIXTRA ® 7.5 MG /0.6 MLSulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Products: VESSEL DUE F, VESSEL DUE F 250 LSU CAPSULEAndexanet alfa
go.drugbank.com/drugs/DB14562ApprovedIt displayed high affinity (0.53–1.53 nmol/L) to apixaban, betrixaban, edoxaban and rivaroxaban [A35518]. … However, the use of these agents is associated with a risk for uncontrollable bleeding episodes that can lead to can cause serious or fatal bleeding.
Categories: Factor XSynonyms: r-Antidote