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PF-06835919
go.drugbank.com/drugs/DB19163InvestigationalPF-06835919 is under investigation in clinical trial NCT05463575 (Ketohexokinase Inhibition in NAFLD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesPf-04531083
go.drugbank.com/drugs/DB12468InvestigationalPf-04531083 has been investigated for the treatment of Pain and Chronic Pain.
LB-P8
go.drugbank.com/drugs/DB18535InvestigationalLB-P8 is an investigational live biotherapeutic product consisting of a single bacterial strain (_Leuconostoc citreum_).
PD-217014
go.drugbank.com/drugs/DB12493InvestigationalPD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome.
Depemokimab
go.drugbank.com/drugs/DB18846ApprovedInvestigationalDepemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug. Its long duration of action is granted by seven amino acid substitutions in the heavy chain sequence. Depemokimab blocks interleukin-5 (IL-5)...
Undecylenic acid
go.drugbank.com/drugs/DB11117ApprovedUndecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aro...
Follitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalHowever, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but
Pemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalWith increasing research on the pathogenesis of cholangiocarcinoma and potential therapeutic targets for anticancer drug treatment, recent studies show that up to 45% of patients with intrahepatic cholangiocarcinoma … It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsVadadustat
go.drugbank.com/drugs/DB12255ApprovedInvestigational[A244165] A relatively new and alternative treatment option for patients with anemia associated with CKD is the use of small molecule inhibitors of hypoxia-inducible factor prolyl-hydroxylase (HIF-PH … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile non-inferior to [darbepoetin alfa] for the treatment of anemia in patients with CKD undergoing dialysis
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Enzyme Inducers