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Dihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigational[A239569] The recently approved Precision Olfactory Delivery technology developed by Impel Neuropharma technology has correlated with an increase of 3-fold in Cmax and 4-fold in AUC despite the solution … formulated at 75% of the strength of the existing intranasal product.
Synonyms: 5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trioneCategories: Heterocyclic Compounds with 4 or More Rings, Serotonin 5-HT1 Receptor AgonistsPapain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnPapain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and _Vasconcellea cundinamarcensis_. … While it has been used for the treatment of inflammation and pain via topical administration, papain has also shown to have anthelmintic and tooth-whitening properties.
Mixtures: Herbalax Forte No 70 Tab, NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADETProducts: Papaya Enzyme - Tablet 30 mg, NORIPAPAIN 10 000 USP UNITS TABLETGadobenic acid
go.drugbank.com/drugs/DB00743ApprovedInvestigationalGadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.
Mixtures: MULTIHANCE INJECTION 10 ML, MULTIHANCE INJECTION 10 MLCategories: Compounds used in a research, industrial, or household settingDoripenem
go.drugbank.com/drugs/DB06211ApprovedWithdrawnIn a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates … , resulting in a premature termination of the trial.
Categories: Heterocyclic Compounds, 2-RingProducts: REDIDOR 500 MG /VIAL, DOREXTRA® DORIPENEM 500 MGGlibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesProducts: GLUTRIL 25MG TABLET, 100 ADET, GLUTRIL 25MG TABLET, 50 ADETSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalIt is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. … in December 2022 for the treatment of flares in adult patients with generalized pustular psoriasis.
Products: Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADETNicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalMost animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. … An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra.
Mixtures: MOL-IRON PANEM 500 MG, Stress B With 1000 Mg Vitamin CCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsRasburicase
go.drugbank.com/drugs/DB00049ApprovedInvestigationalRasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Products: FASTURTEC 7,5 MG/5 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1ADET, FASTURTEC®1.5 MG / MLHexylresorcinol
go.drugbank.com/drugs/DB11254ApprovedIt can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. … It exhibits antiseptic, anthelmintic, and local anesthetic properties.
Synonyms: 4-hexylresorcinol, 4-hexyl-1,3-benzenediolProducts: -s.miel Et Eucalypt., สเตร็ปซิลแมกซ์ (เฮกซิลเรซอซินอล 2.4 มก.)Cholestyramine
go.drugbank.com/drugs/DB01432ApprovedInvestigationalCholestyramine resin is quite hydrophilic, but insoluble in water.
Categories: Compounds used in a research, industrial, or household settingProducts: ANTILIP GRANULADO EN SACHET, ESTRAMIN TOZ, 50 ADET