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Displaying results 141 - 150 of 7657 in total
  1. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineCategories: Non-Selective Monoamine Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  2. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    The harvested product is concentrated and purified by a series of chromatography steps. … acids with an approximate molecular mass of 170 kDa, comprising the FVIII domains A1-A2 + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and replaced by

    Products: NUWIQ 500 UI, NUWIQ 2000 UI
  3. Drug

    Corifollitropin alfa

    go.drugbank.com/drugs/DB09066
    ApprovedInvestigational

    This means that it is made by cells into which a DNA has been introduced that makes them able to produce corifollitropin alfa [L2270]. … Corifollitropin alfa is produced by a method known as ‘recombinant DNA technology’.

    Products: GONAL -F ® INYECTOR 450 UI (33MCG)/0.75ML., GONAL-F ® INYECTOR 900 UI (66 MCG)/1.5 ML
  4. Drug

    Tegoprubart

    go.drugbank.com/drugs/DB16974
    Investigational

    Synonyms: Humanized Anti-Cd40Lg Igg1, Kappa Monoclonal Antibody With Heavy Chain C220S/C226S/C229S/P238S Substitutions To Attenuate Effector Function
  5. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Moroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain, which has no known biological function. … Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia

    Products: XYNTHA® 2000 UI, XYNTHA® 250 UI POLVO LIOFILIZADO PARA SOLUCION INYECTABLE
  6. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    [A228013] Despite a wide variety of functions, exogenous vasopressin is primarily used to control blood pressure during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]

    Products: VASOPRESINA 20 UI/ML, VASOPRESSIN INJECTION USP 20 u/ml
  7. Drug

    L-2-amino-4-methoxy-cis-but-3-enoic acid

    go.drugbank.com/drugs/DB03611
    Experimental

    Synonyms: L-2-amino-4-methoxy-cis-but-3-enoic acid
  8. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.

    Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoinProducts: NEO FURADANTIN, Nu-nitrofurantoin Tablets
  9. Indication

    No more than 2 prior chemotherapy regimens

    go.drugbank.com/conditions/DBCOND0128348
    Drugs: Bevacizumab
    Synonyms: No more than 2 prior chemotherapy regimens
  10. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurr...

    Mixtures: NuDroxiPAK N-500, N-LABS SOLAR MAX Topical AnalgesicSynonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamide