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Displaying results 141 - 150 of 7639 in total
  1. Drug

    3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol

    go.drugbank.com/drugs/DB07079
    Experimental

    Synonyms: 3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol
  2. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    [A185138] It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. … [L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444]

    Mixtures: VALSARTAN HCT MK 80 MG/12.5 MG COMPRIMIDOS RECUBIERTOS, NEO-LOTAN PLUSCategories: Non Potassium Sparing Diuretics
  3. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate is a synthetic glucocorticoid [FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications [FDA Label]. Fluticasone propionate was first approved in...

    Mixtures: FLUTIFORM K HALER 50/5UG, FLUTIFORM K HALER 125/5UGCategories: Agents to Treat Airway Disease
  4. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    The compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.

    Products: LIQUIGEL UD 2.5MG/G EINZEL
  5. Drug

    Eftrenonacog alfa

    go.drugbank.com/drugs/DB11608
    Approved

    It is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding … Eftrenonacog alfa treatment demonstrated good tolerability with no reports of inhibitor development in clinical studies [A31556].

    Products: ALPROLIX® 250 UI
  6. Drug

    Heparin

    go.drugbank.com/drugs/DB01109
    ApprovedInvestigational

    Furthermore, the effects of UH can typically be reversed by using protamine sulfate. … Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da.

    Products: Hep-Lock U/P, HEPARINASODICA USP 25000 UI/5 ML
  7. Drug

    Volanesorsen

    go.drugbank.com/drugs/DB15067
    Approved

    [L16621] Volanesorsen was granted a conditional approval by the European Medicines Agency.[L16621] … [L16621] This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high risk for pancreatitis, who have had inadequate response to triglyceride lowering therapy.

    Products: Na
  8. Drug

    BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE

    go.drugbank.com/drugs/DB08028
    Experimental

    Synonyms: BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE
  9. Drug

    (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMINO]BUT-2-ENYL}OXY)PHENYL]METHANONE

    go.drugbank.com/drugs/DB08458
    Experimental

    Synonyms: (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMINO]BUT-2-ENYL}OXY)PHENYL]METHANONE
  10. Drug

    Pralatrexate

    go.drugbank.com/drugs/DB06813
    ApprovedInvestigational

    [A246703] Pralatrexate was approved by the FDA on September 24, 2009. … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes.

    Synonyms: (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid