Search

Displaying results 141 - 150 of 10000 in total
  1. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.

    Mixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%, SYNERGAL® DOBLECategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  2. Drug

    Lomifylline

    go.drugbank.com/drugs/DB18002
    Approved

    Synonyms: 7-(5-oxohexyl)theophyllineCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Capecitabine

    go.drugbank.com/drugs/DB01101
    ApprovedInvestigational

    Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate, pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
  4. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. … Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
  5. Drug

    5-fluorouridine

    go.drugbank.com/drugs/DB01629
    Investigational

    5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. … FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

    Synonyms: 5-Fur, 5-Fluoro-uridineCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    5-androstenedione

    go.drugbank.com/drugs/DB01456
    ExperimentalIllicit

    Thus 5-androstenedione is a controlled substance, and its use in athletes is prohibited by The World Anti-Doping Agency. … 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors.

    Synonyms: androst-5-ene-3,17-dione, 5-Androstene-3,17-dioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    5-fluorotryptophan

    go.drugbank.com/drugs/DB03314
    Experimental

    5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.

    Synonyms: 5-fluoro-L-tryptophan, L-5-fluorotryptophan
  8. Drug

    5-Hydroxymethylfurfural

    go.drugbank.com/drugs/DB12298
    Investigational

    Aes-103 has been used in trials studying the treatment and prevention of Hypoxia, Anemia, Sickle Cell, and Sickle Cell Disease.

    Synonyms: 5-(Hydroxymethyl)-2-furfural, 5-(hydroxymethyl)-2-furaldehydeCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    5-Methoxybenzimidazole

    go.drugbank.com/drugs/DB04130
    Experimental

    Synonyms: 5-Methoxybenzimidazole
  10. Drug

    5-Nitroindazole

    go.drugbank.com/drugs/DB04534
    Experimental

    Synonyms: 5-Nitroindazole, 5-Nitro-1H-indazoleCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring