5-androstenedione

DB01456ExperimentalIllicitSmall molecule

5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... Thus 5-androstenedione is a controlled substance, and its use in athletes is prohibited by The World Anti-Doping Agency.

Mechanism: Pharmacologically active on Androgen receptor, Estrogen receptor beta, and Steroid Delta-isomerase
Curator reviewed
Formula / weight: C₁₉H₂₆O₂ · 286.415 g/mol (avg)
Code names: J79.661A · NSC-12873

Resolves to

Compound

UNIIHEE11L5C3GCAS571-36-8ChEMBLCHEMBL1743203ChEBI83865PubChem160531KEGGC20252

Structure

InChIKeySQGZFRITSMYKRH-QAGGRKNESA-NSMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2CC(=O)CC[C@]12C

Targets

P10275AR Q92731ESR2P07445ksiP00947ksi

What you can answer from here — as of September 13, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

170Drug interactionsStructured to mechanism, not free text

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with 5-androstenedione, and which of those have an active Phase 3 trial?

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