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Miconazole
go.drugbank.com/drugs/DB01110ApprovedInvestigationalVet approvedDespite having been in clinical use for an extended period, resistance to miconazole among susceptible organisms is relatively low.[A203636] … [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseNonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalIt is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation.
Procaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedBenzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalTinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin III (ATIII). This complex greatly accelerates the inhibition of factor Xa.
Dibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalDibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. In 2004, it was approved by the FDA and is marketed as Infuse. … Through enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and reduces the need for secondary intervention [A31945].
Categories: Drugs for Treatment of Bone DiseasesOxethazaine
go.drugbank.com/drugs/DB12532ApprovedWithdrawn[A33104] Oxetacaine is approved by Health Canada since 1995 for its use as an antacid combination in over-the-counter preparations.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseMeningococcal polysaccharide vaccine group A
go.drugbank.com/drugs/DB13889ApprovedInvestigationalMeningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis a...
Mixtures: MENVEO POWDER & SOLUTION FOR SOLUTION FOR INJECTION, Menveo Powder and Solution for Solution for InjectionFactor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalFor people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and prevention of bleeding episodes … Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation
Gramicidin D
go.drugbank.com/drugs/DB00027ApprovedInvestigationalGramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively grami...
Mixtures: Polysporin for Kids, Antibiotic Cream for KidsCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalIt is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults.
Categories: Antipsoriatics for Topical Use