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Ticlopidine
go.drugbank.com/drugs/DB00208ApprovedTiclopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: TACRON TABLET 250 mg, TICLID 250 MG TABLET, 30 ADETEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalThe sodium salt has been also used to treat primary pulmonary hypertension.
Synonyms: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidProducts: VELETRI® 1.5 MG, VELETRI®0.5 MGSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigational[L7123] Selinexor was also granted accelerated approval for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) that have gone through at least 2 lines of … [L10145] The use of selinexor in combination with [bortezomib] and [dexamethasone] was approved by Health Canada in June 2022 for the treatment of multiple myeloma in adult patients who have received at
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 20 TABLET, Nexpovio 20 mg Film Kaplı Tablet, 8 TABLETCarglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalCarglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.
Products: PERLUGA 200 MG DAĞILABİLİR TABLET, 5 ADET, Kargoced 200 mg Dağılabilir Tablet, 5 ADETThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnIt has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2-Thio-5-ethyl-5-sec-pentylbarbituric acid, 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dioneMifepristone
go.drugbank.com/drugs/DB00834ApprovedInvestigationalAs a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MIFEPRISTONA 200 MG, MIFEPRISTONE 200 MGExametazime
go.drugbank.com/drugs/DB11179ApprovedIt acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex.
Products: CERETEC FOR INJECTION 0.5 mg/vial, CERETEC ESTABILIZADO KIT DE 500 MICROGRAMOS PARA PREPARACIÓN RADIOFARMACÉUTICAIxabepilone
go.drugbank.com/drugs/DB04845ApprovedInvestigationalIxabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. … It has a lactone–lactam modification that minimizes susceptibility to esterase degradation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: IXEMPRA (FOR INJECTION 15 MG), IXEMPRA FOR INJECTION 15 MGVibrio cholerae CVD 103-HgR strain live antigen
go.drugbank.com/drugs/DB14443ApprovedInvestigational_Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against _Vibrio cholerae_ serogroup O1. … [A244489] The FDA approved the cholera vaccine containing _Vibrio cholerae_ CVD 103-HgR strain live antigen under the brand name Vaxchora in June 2016, making it the first vaccine indicated for cholera
Synonyms: Vibrio cholerae CVD 103-HgR strain live antigenLevamlodipine
go.drugbank.com/drugs/DB09237ApprovedInvestigational[L10833] As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity. … [A188940] Levamlodipine was granted FDA approval on 19 December 2019.[L10833]
Mixtures: VOLTRAMOS 5 MG/160 MG FILM KAPLI TABLET, 28 ADET, ALENCAL IRBE® 2.5/150 MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates